The role of Sirtuin1 in non-small cell lung cancer, NSCLC
Potential molecular mechanisms included in the loop (KIAA1967/DBC1 -HIC1 - SIRT1 - p53) dysregulation.
Category
Projekti Hrvatske zaklade za znanost
Principal investigator
Proposed goals of the Project:
a) investigating molecular mehcanisms of dysregulated molecular loop: KIAA1967/DBC1-HIC1-SIRT1-p53, in vitro;
b) Investigating functional consequences of selective SIRT1 silencing, in vitro.