Faculty of Science, University of Zagreb (2016. - 2021.)

• PhD in chemistry, Chemistry department
• Doctoral thesis: "Computational investigation of the mechanism of the irreversible inhibition of the monoamine oxidase B enzyme", thesis supervisor Dr. Robert Vianello

Faculty of Pharmacy and Biochemistry, University of Zagreb (2011. - 2016.)

• Master od medicinal chemistry
• Master thesis: "Mechanism of chlorination reaction between 5-fluorouracil." thesis supervisor Dr. Valerije Vrček
• Student practice at Department of Medicinal Chemistry, University Hospital for Tumors, Zagreb (Croatia)

XV. gymnasium, Zagreb (2007.-2011.) 

Elemetary school OŠ Murterski škoji, Murter (1999.-2007.)

2022 Award for a young scientist in the field of medicinal and pharmaceutical chemistry  (Croatian Chemical Society, Selvita d.o.o.)
2021 Scholarship of the Austrian Academy of Arts and Sciences (JESH - Croatia) for a stay of six months in Max Perutz labs (Vienna, Austria)

Annual Ruđer Bošković Institute award for published scientific paper in 2019 and 2020

2019 Thiene poster award, 16th European Symposium of Organic Reactivity, Dubrovnik

2019 French Government Scholarship for a one-month stay at the Sorbonne University (Paris, France).

Recipient of the Annual Dean's Award for Scientific Work "Chlorination of N-Methylacetamide and Amide-Containing Pharmaceuticals. Quantum- Chemical Study of the Reaction Mechanism. " published in scientific Journal of Physical Chemistry A for the academic year 2013/2014.

Recipient of the Annual Dean's Award for Student Research "The chemical fate of antiepileptics neutrophile. In silico research of reaction mechanism with hypochlorous acid ." for the academic year 2014/2015.

Molecular and Statistical Mechanics , Computational Lab,  Uppsala University (Sweden), 2022-2024.

General chemistry with stoichiometry, seminars, Faculty of Pharmacy and Biochemistry, University of Zagreb (Croatia), 2019/2020.

Izvorni znanstveni rad

• Pavić, Kristina; Poje, Goran; Pessanha de Carvalho, Lais; Tandarić, Tana; Marinović, Marina; Fontinha, Diana; Held, Jana; Prudêncio, Miguel; Piantanida, Ivo; Vianello, Robert et al. | Discovery of harmiprims, harmine-primaquine hybrids, as potent and selective anticancer and antimalarial compounds // Bioorganic & medicinal chemistry, 105 (2024), 117734, 16. doi: 10.1016/j.bmc.2024.117734

  doi

• Prieto-Díaz, Rubén; Fojo-Carballo, Hugo; Majellaro, Maria; Tandarić, Tana; Azuaje, Jhonny; Brea, José; Loza, María I.; Barbazán, Jorge; Salort, Glòria; Chotalia, Meera et al. | Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents // Biomedicine & pharmacotherapy, 173 (2024), 116345, 27. doi: 10.1016/j.biopha.2024.116345

  doiwww.sciencedirect.com

• Matić, Josipa ; Tandarić, Tana ; Radić Stojković, Marijana ; Šupljika, Filip ; Karačić, Zrinka ; Tomašić Paić, Ana ; Horvat, Lucija ; Vianello, Robert ; Tumir, Lidija-Marija | Phenanthridine–pyrene conjugates as fluorescent probes for DNA/RNA and an inactive mutant of dipeptidyl peptidase enzyme // Beilstein journal of organic chemistry, 19 (2023), 550-565. doi: 10.3762/bjoc.19.40

  doiwww.beilstein-journals.orgfulir.irb.hr

• Pantalon Juraj, Natalija ; Tandarić, Tana ; Tadić, Vanja ; Perić, Berislav ; Moreth, Dominik ; Schatzschneider, Ulrich ; Brozovic, Anamaria ; Vianello, Robert ; Kirin, Srećko I. | Tuning the coordination properties of chiral pseudopeptide bis(2-picolyl)amine and iminodiacetamide ligands in Zn(II) and Cu(II) complexes // Dalton transactions, 51 (2022), 44; 17008-17021. doi: 10.1039/d2dt02895f

  doipubs.rsc.org

• Poje, Goran ; Pessanha de Carvalho, Lais ; Held, Jana ; Moita, Diana ; Prudêncio, Miguel ; Perković, Ivana ; Tandarić, Tana ; Vianello, Robert ; Rajić, Zrinka | Design and synthesis of harmiquins, harmine and chloroquine hybrids as potent antiplasmodial agents // European journal of medicinal chemistry, 238 (2022), 114408, 15. doi: 10.1016/j.ejmech.2022.114408

  doiwww.sciencedirect.comdoi.org

• Marinović, Marina ; Poje, Goran ; Perković, Ivana ; Fontinha, Diana ; Prudêncio, Miguel ; Held, Jana ; Pessanha de Carvalho, Lais ; Tandarić, Tana ; Vianello, Robert ; Rajić, Zrinka | Further investigation of harmicines as novel antiplasmodial agents: synthesis, structure-activity relationship and insight into the mechanism of action // European journal of medicinal chemistry, 224 (2021), 113687, 20. doi: 10.1016/j.ejmech.2021.113687

  doiwww.sciencedirect.comdoi.org

• Matić, Josipa ; Jukić, Marijana ; Ismaili, Hamit ; Saftić, Dijana ; Ban, Željka ; Tandarić, Tana ; Vianello, Robert ; Opačak-Bernardi, Teuta ; Glavaš-Obrovac, Ljubica ; Žinić, Biserka | 6-Morpholino- and 6-amino-9-sulfonylpurine derivatives. Synthesis, computational analysis, and biological activity // Nucleosides, nucleotides & nucleic acids, 40 (2021), 4; 470-503. doi: 10.1080/15257770.2021.1896001

  doiwww.tandfonline.comdoi.org

• Marinović, Marina ; Perković, Ivana ; Fontinha, Diana ; Prudêncio, Miguel ; Held, Jana ; Pessanha de Carvalho, Lais ; Tandarić, Tana ; Vianello, Robert ; Zorc, Branka ; Rajić, Zrinka | Novel Harmicines with Improved Potency against Plasmodium // Molecules, 25 (2020), 19; 4376, 19. doi: 10.3390/molecules25194376

  doiwww.mdpi.comfulir.irb.hr

• Tandarić, Tana ; Prah, Alja ; Stare, Jernej ; Mavri, Janez ; Vianello, Robert | Hydride Abstraction as the Rate-Limiting Step of the Irreversible Inhibition of Monoamine Oxidase B by Rasagiline and Selegiline: A Computational Empirical Valence Bond Study // International journal of molecular sciences, 21 (2020), 17; 6151, 13. doi: 10.3390/ijms21176151

  doifulir.irb.hrwww.mdpi.com

• Rimac, Hrvoje ; Tandarić, Tana ; Vianello, Robert ; Bojić, Mirza | Indomethacin increases quercetin affinity for human serum albumin: a combined experimental and computational study and its broader implications // International journal of molecular sciences, 21 (2020), 16; 5740, 14. doi: 10.3390/ijms21165740

  doiwww.mdpi.comdoi.orgfulir.irb.hr

• Perković, Ivana ; Raić-Malić, Silvana ; Fontinha, Diana ; Prudêncio, Miguel ; Pessanha de Carvalho, Lais ; Held, Jana ; Tandarić, Tana ; Vianello, Robert ; Zorc, Branka ; Rajić, Zrinka | Harmicines − harmine and cinnamic acid hybrids as novel antiplasmodial hits // European journal of medicinal chemistry, 187 (2020), 111927, 16. doi: 10.1016/j.ejmech.2019.111927

  doidoi.orgwww.sciencedirect.com

• Tandarić, Tana ; Hok, Lucija ; Vianello, Robert | From Hydrogen Peroxide-Responsive Boronated Nucleosides Towards Antisense Therapeutics – A Computational Mechanistic Study // Croatica chemica acta, 92 (2019), 2; 287-295. doi: 10.5562/cca3592

  doihrcak.srce.hrdoi.orgfulir.irb.hr

• Toma, Mateja ; Božičević, Lucija ; Lapić, Jasmina ; Djaković, Senka ; Šakić, Davor ; Tandarić, Tana ; Vianello, Robert ; Vrček, Valerije | Transacylation in Ferrocenoyl-Purines. NMR and Computational Study of the Isomerization Mechanism // Journal of organic chemistry, 84 (2019), 19; 12471-12480. doi: 10.1021/acs.joc.9b01944

  doidoi.orgpubs.acs.org

• Tandarić, Tana ; Vianello, Robert | Computational Insight into the Mechanism of the Irreversible Inhibition of Monoamine Oxidase Enzymes by the Antiparkinsonian Propargylamine Inhibitors Rasagiline and Selegiline // ACS Chemical Neuroscience, 10 (2019), 8; 3532-3542. doi: 10.1021/acschemneuro.9b00147

  doipubs.acs.orgdoi.orgfulir.irb.hr

• Matić, Josipa ; Šupljika, Filip ; Tandarić, Tana ; Dukši, Marko ; Piotrowski, Patryciusz ; Vianello, Robert ; Brozović, Anamaria ; Piantanida, Ivo ; Schmuck, Carsten ; Radić Stojković, Marijana | DNA/RNA recognition controlled by the glycine linker and the guanidine moiety of phenanthridine peptides // International journal of biological macromolecules, 134 (2019), 422-434. doi: 10.1016/j.ijbiomac.2019.05.063

  doiwww.sciencedirect.comdoi.orgfulir.irb.hr

• Hok, Lucija ; Ulm, Lea ; Tandarić, Tana ; Krivohlavek, Adela ; Šakić, Davor ; Vrček, Valerije | Chlorination of 5-fluorouracil: Reaction mechanism and ecotoxicity assessment of chlorinated products // Chemosphere, 207 (2018), 18; 612-619. doi: 10.1016/j.chemosphere.2018.05.140

  doiwww.sciencedirect.com

• Tandarić, Tana ; Vianello, Robert | Design of Exceptionally Strong Organic Superbases Based on Aromatic Pnictogen Oxides: Computational DFT Analysis of the Oxygen Basicity in the Gas Phase and Acetonitrile Solution // The journal of physical chemistry. A, 122 (2018), 5; 1464-1471. doi: 10.1021/acs.jpca.7b11945

  doipubs.acs.org

• Dabić, Dario ; Brkljačić, Lidija ; Tandarić, Tana ; Žinić, Mladen ; Vianello, Robert ; Frkanec, Leo ; Kobetić, Renata | The Metal effect on self-assembling of oxalamide gelators explored by mass spectrometry and DFT calculations // Journal of the American Society for Mass Spectrometry, 28 (2018), 1; 103-113. doi: 10.1007/s13361-017-1834-5

  doidx.doi.orglink.springer.com

• Tandarić, Tana ; Vrček, Valerije ; Šakić, Davor | Quantum Chemical Study of HOCl-Induced Transformations of Carbamazepine // Organic & biomolecular chemistry, 14 (2016), 10866-10874. doi: 10.1039/C6OB02166B

  doipubs.rsc.org

• Šakić, Davor ; Šonjić, Pavica ; Tandarić, Tana ; Vrček, Valerije | Chlorination of N-Methylacetamide and Amide-Containing Pharmaceuticals : Quantum-Chemical Study of the Reaction Mechanism // The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical, 118 (2014), 12; 2367-2376. doi: 10.1021/jp5012846

  doipubs.acs.orgpubs.acs.org

Sažetak izlaganja sa skupa

• Tandarić, Tana; Gutierrez de Teran, Hugo | Discovery of allosteric modulators of A2A receptors // 10th EFMC Young Medicinal Chemists' Symposium - Book of Abstracts / Beus, Maja; Alker, David; Eshak, Floriane et al. (ur.). | Louvain-la-Neuve, Wallonia, Belgium: European Federation for Medicinal chemistry and Chemical biology (EFMC), 2023. str. 24-24

• Tandarić, Tana; Gutierrez de Teran, Hugo | Discovery of allosteric modulators of A2A receptors // IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry: Book of Abstracts / Gademann, Karl; Hartung, Ingo (ur.). | Louvain-la-Neuve, Wallonia, Belgium: European Federation for Medicinal chemistry and Chemical biology (EFMC), 2023. str. 322-322

• Boček Pavlinac, Ida ; Hok, Lucija ; Tandarić, Tana ; Hranjec, Marijana ; Vianello, Robert | Photophysical and computational study of iminocoumarin and imidazo[4,5-b]pyridines conjugates as novel pH sensitive probes // 28th Croatian Meeting of Chemists and Chemical Engineers (28HSKIKI): Book of Abstracts / Rogošić, Marko (ur.). | Zagreb: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2023. str. 142-142

  www.hdki.hr

• Tandarić, Tana ; Vianello, Robert | An insight into the mechanism of the irreversible inhibition of monoamine oxidase enzymes by propargylamine inhibitors // 12th JMMC – Joint meeting on medicinal chemistry: book of abstracts. | Bratislava: Slovenská toxikologická spoločnosť SETOX, 2022. str. 29-29

• Boček, Ida ; Hok, Lucija ; Tandarić, Tana ; Hranjec, Marijana ; Vianello, Robert | Design and Development of Novel pH-Sensors Based on Iminocoumarin Derived Imidazo[4,5-b]pyridines // Computational Chemistry Day 2022 : Book of Abstracts. | Zagreb: Institut Ruđer Bošković, 2022. str. 47-47

• Rajić, Zrinka ; Poje, Goran ; Pessanha de Carvalho, Lais ; Held, Jana ; Perković, Ivana ; Tandarić, Tana ; Vianello, Robert | Harmiquins, novel potent antiplasmodial hits // 9th BBBB International Conference on Pharmaceutical Sciences, Book of Abstracts. | Ljubljana: Slovensko farmacevtsko društvo in Univerza v Ljubljani, Fakulteta za farmacijo, 2022. str. 224-225

  bbbb2022.sfd.si

• Hok, Lucija ; Ulm, Lea ; Tandarić, Tana ; Krivohlavek, Adela ; Šakić, Davor ; Vrček, Valerije | Chlorination of 5-Fluorouracil: Reaction Mechanism and Ecotoxicity Assessment of Chlorinated Products // Computational Chemistry Day : Book of Abstracts. | Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2018. str. 24-24

  www.pmf.unizg.hr

• Hok, Lucija ; Tandarić, Tana ; Šakić, Davor ; Vrček, Valerije | Mehanizam reakcije kloriranja 5-fluorouracila i ekotoksikološka analiza kloriranih produkata // 4. Simpozij studenata kemičara : Knjiga sažetaka. | Zagreb: Studentska sekcija HKD, 2017. str. 17-17

  www.hkd.hr

• Tandarić, Tana ; Vianello, Robert | A computational insight into the mechanism of the irreversible inhibition of monoamine oxidase enzymes by the antiparkinsonian propargylamine inhibitors rasagiline and selegiline // 18th Hellenic Symposium on Medicinal Chemistry : Abstract Book. | 2021, 133, 1

• Toma, Mateja ; Božičević, Lucija ; Tandarić, Tana ; Vianello, Robert ; Šakić, Davor ; Vrček, Valerije | Reakcijski mehanizam transaciliranja ferocenoil-purina. Računalna studija // 8. Simpozij studenata farmacije i medicinske biokemije, FARMEBS 2019. - Knjiga Sažetaka. | Zagreb: Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu, 2019. str. 34-34

  drive.google.com

• Tandarić, Tana ; Vianello, Robert | Irreversible inhibition of the MAO B enzyme. A computational insight into the inactivation mechanism // 17th European Symposium on Organic Reactivity (ESOR 2019), Book of abstracts. | Zagreb: Hrvatsko kemijsko društvo, 2019. str. 92-92

  esor.chem.pmf.hrwww.bib.irb.hr

• Tandarić, Tana ; Vianello, Robert | Computational insight into the MAO B enzyme irreversible inhibition // Computational Chemistry Day 2019, Book of abstracts. | Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2019. str. 9-9

  ccd19.pharma.hr

• Tandarić, Tana ; Robert Vianello | Irreversible inhibition of monoamine oxidase B enzyme. A computational insight. // Book of abstracts - 5th EFMC Young Medicinal Chemist Symposium.. | 2018. str. 112-112

• Tandarić, Tana ; Vianello Robert | Irreversible inhibition of monoamine oxidase B enzyme. A computational insight. // Book of abstracts EFMC-ISMC 2018 XXV EFMC International Symposium on Medicinal Chemistry.. | 2018. str. 417-417

• Tandarić, Tana ; Vianello, Robert | RAČUNALNI UVID U IREVERZIBILNU INHIBICIJU ENZIMA MONOAMINOOKSIDAZE B // Knjiga sažetaka 2. Simpozija doktorskih studija PMF-a.. | Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2018. str. 38-38

• Vrček, Valerije ; Hok, Lucija ; Šakić, Davor ; Toma, Mateja ; Djaković, Senka ; Lapić, Jasmina ; Tandarić, Tana | Mechanistic insights into chemical reactions via “in situ” NMR // Adriatic NMR Conference : Book of abstracts. | Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2018. str. 37-37

  adriatic-nmr-conference.chem.pmf.hr

• Tandarić, Tana ; Vianello, Robert | Irreversible inhibition of monoamine oxidase B enzyme. A computational insight // Computational Chemistry Day : Book of Abstracts. | Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2018. str. 32-32

  www.pmf.unizg.hr

• Tandarić, Tana ; Vianello, Robert | Computational insight into the cyclotrimerization of isocyanates using bicyclic guanidine catalyst // 25. Hrvatski skup kemičara i kemijskih inženjera s međunarodnim sudjelovanjem ; 3. simpozij Vladimir Prelog : knjiga sažetaka = 25th Croatian Meeting of Chemist and Chemical Engineers with international participation. 3rd symposium “Vladimir Prelog” : Book of Abstracts. | Zagreb: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI) ; Hrvatsko kemijsko drustvo, 2017. str. 81-81

  drive.google.comwww.hdki.hr

• Tandarić, Tana ; Vianello, Robert | Novel and efficient bicyclic guanidine catalyst for the cyclotrimerization of isocyanates : a quantum chemical study // Book of Abstracts of the 10th Joint Meeting on Medicinal Chemistry. | Zagreb: Hrvatsko kemijsko društvo, 2017. str. 226-226

• Petrović Peroković, Vesna ; Car, Željka ; Meglić, Karlo ; Ribić, Rosana ; Tandarić, Tana ; Vianello, Robert ; Tomić, Srđanka | Novel para substituted n-aryl 3-hydroxypyridin- 4-one mannosides: synthesis, hemagglutination inhibitory properties and molecular modeling // Book of Abstracts of the 10th Joint Meeting on Medicinal Chemistry. | Zagreb: Hrvatsko kemijsko društvo, 2017. str. 119-119

• Hok, Lucija ; Pem, Barbara ; Tandarić, Tana ; Šakić, Davor ; Vrček, Valerije | Kloriranje barbiturata. Kvantno - kemijska studija reakcijskog mehanizma // 6. simpozij studenata farmacije i medicinske biokemije : knjiga sažetaka. | Zagreb: Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu, 2017. str. 56-56

• Tandarić, Tana ; Hok, Lucija ; Šakić, Davor ; Vrček, Valerije | Mehanizam reakcije između 5-fluorouracila i hipokloraste kiseline // 6. simpozij studenata farmacije i medicinske biokemije : Knjiga sažetaka. | Zagreb: Zinam d.o.o., 2017. str. 20-20

  drive.google.com

• Hok, Lucija ; Pem, Barbara ; Tandarić, Tana ; Šakić, Davor ; Vrček, Valerije | The chlorination of barbiturates. Quantum-chemical study of the reaction mechanism // 25. Hrvatski skup kemičara i kemijskih inženjera s međunarodnim sudjelovanjem ; 3. simpozij Vladimir Prelog : knjiga sažetaka = 25th Croatian Meeting of Chemist and Chemical Engineers with international participation. 3rd symposium “Vladimir Prelog” : Book of Abstracts. | Zagreb: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI) ; Hrvatsko kemijsko drustvo, 2017. str. 115-115

  drive.google.comwww.hdki.hr

• Šonjić, Pavica ; Tandarić, Tana ; Šakić, Davor ; Vrček, Valerije | Utjecaj supstituenata na reaktivnost derivata barbiturne kiseline s hipoklornom kiselinom // 5. hrvatski kongres farmacije s međunarodnim sudjelovanjem. Farmaceutska izvrsnost u službi zdravlja.. | Rovinj: Hrvatsko farmaceutsko društvo, 2015. str. 165-165

  http

• Šakić, Davor ; Tandarić, Tana ; Vrček, Valerije | Why Hypochlorous Acid Chlorinates Amines Rather than Hydroxylates Them // 15th European Symposium of Organic Reactivity, Book of Abstracts. | Kiehl, 2015. str. 165-165

  www.esor2015.org

• Šonjić, Pavica ; Tandarić, Tana ; Šakić, Davor ; Vrček, Valerije | Influence of Various Moieties on Resistance of Derivatives of Barbituric Acid in Reaction of Chlorination with Hypochlorous Acid. Quantum- Chemical Study. // XXIV. HRVATSKI SKUP KEMIČARA I KEMIJSKIH INŽENJERA Knjiga sažetaka. | Zagreb: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI) ; Hrvatsko kemijsko društvo, 2015. str. 68-68

  www.24hskiki.hr

Neobjavljeni prilog sa skupa

• Tandarić, Tana; Gutierrez de Teran, Hugo | Discovery of allosteric modulators of A2A receptors // ACS FALL 2023 | San Francisco (CA), Sjedinjene Američke Države, 13.08.2023-17.08.2023

Diplomski rad

• Tandarić, Tana | Mehanizam reakcije kloriranja 5-fluorouracila / Vrček, Valerije (mentor). | Zagreb, Farmaceutsko-biokemijski fakultet, 2016

Doktorska disertacija

• Tandarić, Tana | Računalno istraživanje mehanizma ireverzibilne inhibicije enzima monoamin-oksidaze B / Vianello, Robert (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2021

  repozitorij.pmf.unizg.hr

Croatian Chemical Society 2016 - present