This project will analyse state-of-the-art data on three geographically distant medaka populations to unravel the said metabolic adaptations. Coupling the results with population dynamics will further reveal the consequences of such adaptations to whole populations. Particularly important will be implications for aquaculture production aimed at avoiding production losses in the face of a changing climate. The project should therefore be timely and relevant for Croatia as a major aquaculture producer, as well as a country where climate-change-driven temperature increases have already surpassed the 2-degree limit of the Paris Accord.