Kolokvij IRB-a: "Deciphering Microbiota Functionality and Dynamics: A Metaproteomic Perspective"
Pozivamo vas na predavanje u okviru Kolokvija IRB-a: Deciphering Microbiota Functionality and Dynamics: A Metaproteomic Perspective koje će održati dr. sc. Lucia Grenga, Atomic Energy and Alternative Energies Commission, CEA, France. Predavanje će se održati u utorak, 3. prosinca u 10 sati u dvorani III. krila, Institut Ruđer Bošković.
Microbial communities are of significant interest across medical, environmental, and biotechnological fields due to their complex roles and potential applications. However, studying these communities presents considerable challenges, given their complexity and dynamic nature. While early microbiome research primarily focused on cataloging the diversity of microbes within these communities, recent efforts increasingly aim to understand the connections among microbes and how they function. Omics technologies, particularly metaproteomics, are invaluable tools for exploring these intricacies.
Dr. Grenga will begin her talk by introducing how metaproteomics contributes to unveiling the taxonomic composition, temporal shifts, and functional interactions within microbiota. She will present their contributions to the field, including the development of innovative sample preparation methods and mass spectrometry methods, and advanced bioinformatics pipelines. Finally, she will discuss how they leverage these rich datasets to accelerate the translation of microbiome knowledge into real-world
applications.
Lucia Grenga received her Ph.D. in Cellular and Molecular Biology in 2010 and has been a specialist in Clinical Pathology since 2016. She joined the laboratory of
'Innovative technologies for Detection and Diagnostics' (Li2D) of CEA in 2018 as a permanent researcher.
Lucia’s research activity focuses on characterizing clinically relevant microbiota via multi-omics analysis. At Li2D, she has developed multiple research lines investigating
the dynamics and roles of human lung and gut microbiota, with the goal of developing advanced methodologies for the diagnosis and/ or treatment of
microbiome-related human diseases.
She co-leads the ProGénoMix proteomic platform, a cornerstone of ProFI, the French national infrastructure specialized in proteomics. Additionally, Lucia serves on the
board of the Metaproteomics Initiative and as an external expert for the European Commission in the field of public health, clinical medicine, and gut microbiome.