News

Popovic group in collaboration with Ramadan group from Oxford University and Nanyang Technological University in Singapur published in Cell!

Popovic group in collaboration with Ramadan group from Oxford University and Nanyang Technological University in Singapur published in Cell!

Sep 1st 2024

TEMA: Stvaranje SPRTN i TDP deficijentnih animalnih modela pomoću CRISPR/Cas sustava

EMBO poster prize

First paper from the DPC group published in Open Biology! Check out our recent paper on DNA-protein crosslink repair (DPCR) including the first animal model created at Ruder Boskovic Institute, Tdp1-deficient zebrafish strain!

Our new paper on the role of Tyrosyl-DNA phosphodiesterase 2 (Tdp2) in DPC repair is out!

Oct 1st 2023

Our insights into ACRC protease show that it is essential for vertebrate development where it repairs DNA-protein crosslinks including histone-DPCs. You can access the pre-print at: https://www.biorxiv.org/content/10.1101/2023.03.07.531502v1.

Exciting news! Our latest data reveal new mechanism of DNA-protein crosslink repair in vivo, shedding new light on understanding DPC-related diseases and identifying potential chemotherapeutic targets. Check our pre-print 'Tyrosyl-DNA phosphodiesterase 1 (TDP1) and SPRTN protease repair histone 3 and topoisomerase 1 DNA-protein crosslinks in vivo’ at: https://www.biorxiv.org/content/10.1101/2023.03.01.530659v1.

New Phd student joins dr. Popovic group

DNA damage group at Croatian Television and MUZZA science week

Jun 1st 2021

Division for Marine and Environmental Research