Paper by RBI Scientists Published in the American Journal of Pathology
The American Journal of Pathology (IF: 5.22), the leading journal in pathology research, published a paper by RBI scientists Dr. Ivica Kopriva (ZLAIR), Dr. Mirka Hadžija, Dr. Marijana Popović-Hadžija, Dr. Marina Korolija (ZMM) and Dr. Andrzej Cichocki (RIKEN, Japan), entitled "Rational Variety Mapping for Contrast-Enhanced Nonlinear Unsupervised Segmentation of Multispectral Images of Unstained Specimen". One of the results of the study was published on the front page of the journal.
The paper presents a method for enhancing the contrast of the multispectral images of a histopathological specimen of an algorithm of nonlinear segmentation. On two experimental unstained specimens, contrast was achieved comparable to that of a stained specimen. With further refinement, it should be possible to develop methods for the nonlinear segmentation of multispectral images, which would eliminate the need for staining in clinically important applications.
The American Journal of Pathology