Crosslinking of self-assembled fatty acids on copper by electron beam irradiation
Principal investigator
Polymer nanocoatings based on fatty acids have a great potential for biomedical applications. Such coatings can slow down the dissolution of metal-based implants, and fatty acids are biocompatible since they degrade into low-toxic products that are not harmful to the human body. Radiation-induced crosslinking is homogeneous, fast, can be carried out at room temperature without use of solvents, initiators and/or catalysts. If crosslinking is performed using ionizing irradiation the process is clean, and if the doses used are 25 kGy or higher the coatings are simultaneously crosslinked and sterilized. Nevertheless, their crosslinking has been studied and demonstrated only under gamma irradiation conditions, while for commercial applications crosslinking under electron beam technology could be more suitable due to technological parameters such as high dose rate and short irradiation time, or the possibility of irradiation at low temperature. The proposed project will focus on studying the conditions for crosslinking fatty acids on metals using electron beams and grafting vitamin E on the developed polymer coatings.