STIM-REI, a project of the Center of Excellence for Science and Technology - Integration of Mediterranean Region (STIM) connects research (R), innovation (I) and education (E) through three project elements based on the international excellence of scientists and the choice of research directions of key importance for societal needs. The mission is a unique integration of the triangle research - innovation - education. The fundamental guidelines of the Project remove the boundaries between research disciplines and provide a basis for new interdisciplinary research by national and international networking. Our innovation system brings together all aspects of project elements, including long-term cooperation between academia and industry, providing a unique opportunity for the practical application of research results. The STIM-REI project enabled the acquisition of modern equipment as a fundamental condition for internationally competitive and innovative research The results of newly employed young researchers in Croatia are already opening the door to international recognition and long-term success.