dr. sc. Ksenija Zahradka
Bijenička cesta 54
HR-10000 Zagreb
Obrazovanje
1991 Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, dipl. inž. biologije (molekularna biologija)
1994 Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, magistar prirodnih znanosti (molekularna i stanična biologija)
1999 Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, doktor prirodnih znanosti (biologija)
2002 Medicinski fakultet Necker, Sveučilište René Descartes, Pariz, Francuska, poslijedoktorsko usavršavanje (molekularna genetika bakterija, grupa prof. M. Radmana)
Projekti
2023- "Alternativni putevi rekombinacije i popravka DNA u bakterijama Escherichia coli i Deinococcus radiodurans" (HRZZ-IP-2022-10-7476), Hrvatska zaklada za znanost - voditeljica
2017-2022 "Bioprospecting Jadranskog mora" (KK.01.1.1.01), Fond za regionalni razvoj EU, Aktivnost 1: Istraživanje biološke raznolikosti i genetičkih resursa morskih staništa - suradnica
2014-2018 "Rekombinacija, popravak DNA i očuvanje integriteta genoma: novi putevi" (HRZZ-IP-2013-11-2978), Hrvatska zaklada za znanost - suradnica
2011-2015 "Biologija robusnosti", Mediteranski institut za istraživanje života - suradnica
2007-2013 "Molekularni mehanizmi rekombinacije i popravka DNA" (098-0982913-2862), Ministarstvo znanosti, obrazovanja i sporta RH - suradnica
2007-2010 "Život u ekstremnim uvjetima", Mediteranski institut za istraživanje života - suvoditeljica
2002-2006 "Regulacija rekombinacije i rekombinacijskog popravka" (00981002), Ministarstvo znanosti, obrazovanja i sporta RH - suradnica
1997-2001 "Regulacija rekombinacije i rekombinacijskog popravka DNA", Ministarstvo znanosti i tehnologije RH - suradnica
1994-1997 "Genes and enzymes involved in inhibition of recombination" (CRP/CRO93-01), UNIDO/ICGEB - suradnica
Nagrade i priznanja
2007 Državna godišnja nagrada za znanost, za znanstveno otkriće u području prirodnih znanosti
2006 Nagrada za znanstvenu izvrsnost, Ministarstvo znanosti, obrazovanja i sporta RH
2002 Stipendija Instituta Necker (za poslijedoktorsko usavršavanje), Pariz, Francuska
Nastava
Kolegij “Genetička rekombinacija i popravak DNA”, Poslijediplomski doktorski studij biologije, Prirodoslovno-matematički fakultet, Sveučilište u Zagrebu (suvoditeljica)
Kolegij “Mehanizmi oštećenja i popravka DNA”, Interdisciplinarni doktorski studij "Molekularne bioznanosti", Sveučilište u Osijeku, Sveučilište u Dubrovniku i IRB Zagreb (suvoditeljica)
Istaknute publikacije
Zahradka, K., Repar, J., Đermić, D, Zahradka, D. (2023) Chromosome Segregation and Cell Division Defects in Escherichia coli Recombination Mutants Exposed to Different DNA-Damaging Treatments. Microorganisms 11(3):701. doi: 10.3390/microorganisms11030701
Repar, J., Zahradka, D., Sović, I., Zahradka, K. (2021) Characterization of gross genome rearrangements in Deinococcus radiodurans recA mutants. Sci Rep. 11: 10939. doi: 10.1038/s41598-021-89173-9
Buljubašić, M., Hlevnjak, A., Repar, J., Đermić, D., Filić, V., Weber, I., Zahradka, K., Zahradka, D. (2019) RecBCD- RecFOR-independent pathway of homologous recombination in Escherichia coli. DNA Repair 83: 102670. doi: 10.1016/j.dnarep.2019.102670
Repar, J., Supek, F., Klanjscek, T., Warnecke, T., Zahradka, K., Zahradka, D. (2017) Elevated rate of genome rearrangements in radiation-resistant bacteria. Genetics 205: 1677-1689.
Buljubašić, M., Zahradka, D., Zahradka, K. (2013) RecQ helicase acts before RuvABC, RecG and XerC proteins during recombination in recBC sbcBC mutants of Escherichia coli. Res. Microbiol. 164: 987-997.
Buljubašić, M., Repar, J., Zahradka, K., Đermić, D., Zahradka, D. (2012) RecF recombination pathway in Escherichia coli cells lacking RecQ, UvrD and HelD helicases. DNA Repair 11: 419-430.
Repar, J., Cvjetan, S., Slade, D., Radman, M., Zahradka, D., Zahradka, K. (2010) RecA protein assures fidelity of DNA repair and genome stability in Deinococcus radiodurans. DNA Repair 9: 1151-1161.
Zahradka, K., Buljubašić, M., Petranović, M., Zahradka, D. (2009) Roles of ExoI and SbcCD nucleases in "reckless" DNA degradation in recA mutants of Escherichia coli. J. Bacteriol. 191: 1677-1687.
Zahradka, K., Slade, D., Bailone, A., Sommer, S., Averbeck, D., Petranovic, M., Lindner, A. B., Radman, M. (2006) Reassembly of shattered chromosomes in Deinococcus radiodurans. Nature 443: 569-573.
Zahradka, K., Šimić, S., Buljubašić, M., Petranović, M., Đermić, D., Zahradka, D. (2006) sbcB15 and delsbcB mutations activate two types of RecF recombination pathway in Escherichia coli. J. Bacteriol. 188: 7562-7571.
Publikacije - prilozi u knjigama
Izvorni znanstveni rad
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Zahradka, Ksenija ; Zahradka, Davor | Reckless DNA Degradation // Brenner's Encyclopedia of Genetics (2nd ed.). | San Diego (CA): Academic Press, 2013. str. 72-74 . doi: 10.1016/B978-0-12-374984-0.01272-9
doidoi.orgwww.sciencedirect.com Zahradka, Ksenija | Izdvajanje DNA bakteriofaga // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 171-174
Zahradka, Davor ; Zahradka, Ksenija | Prijenos gena transdukcijom pomoću faga P1 // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 919-922-x
Zahradka, Ksenija | Elektroforeza DNA u promjenjivom električnom polju (PFGE) // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 206-209-x
Zahradka, Ksenija | Izdvajanje visokomolekularne genomske DNA za elektroforezu u promjenjivom električnom polju (PFGE) // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 189-191-x
Zahradka, Ksenija | Izdvajanje genomske DNA iz bakterija // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 141-143-x
Publikacije - prilozi u časopisima
Izvorni znanstveni rad
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Pipalović, Goran; Filić, Želimira; Ćehić, Mirsada; Paradžik, Tina; Zahradka, Ksenija; Crnolatac, Ivo; Vujaklija, Dušica | Impact of C-terminal domains of paralogous single-stranded DNA binding proteins from Streptomyces coelicolor on their biophysical properties and biological functions // International journal of biological macromolecules, 268 (2024), Part 1; 131544, 11. doi: 10.1016/j.ijbiomac.2024.131544
doiwww.sciencedirect.com -
Zahradka, Ksenija; Zahradka, Davor; Repar, Jelena | Structural Differences between the Genomes of Deinococcus radiodurans Strains from Different Laboratories // Genes, 15 (2024), 7; 847, 14. doi: 10.3390/genes15070847
doiwww.mdpi.comfulir.irb.hr -
Pipalović, Goran; Filić, Želimira; Ćehić, Mirsada; Paradžik, Tina; Zahradka, Ksenija; Crnolatac, Ivo; Vujaklija, Dušica | Impact of C-terminal domains of paralogous single-stranded DNA binding proteins from Streptomyces coelicolor on their biophysical properties and biological functions // International journal of biological macromolecules, 268 (2024), Part 1; 131544, 1. doi: 10.1016/j.ijbiomac.2024.131544
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Zahradka, Ksenija ; Repar, Jelena ; Đermić, Damir ; Zahradka, Davor | Genetic analysis of transductional recombination in Escherichia coli reveals differences in the postsynaptic stages of RecBCD and RecFOR pathways // Periodicum biologorum, 124 (2022), 3-4; 97-106. doi: 10.18054/pb.v124i3-4.23604
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Zahradka, Ksenija ; Repar, Jelena ; Đermić, Damir ; Zahradka, Davor | Chromosome Segregation and Cell Division Defects in Escherichia coli Recombination Mutants Exposed to Different DNA-Damaging Treatments // Microorganisms, 11 (2023), 3; 11030701, 30. doi: 10.3390/microorganisms11030701
doiwww.mdpi.comfulir.irb.hr -
Repar, Jelena ; Zahradka, Davor ; Sović, Ivan ; Zahradka, Ksenija | Characterization of gross genome rearrangements in Deinococcus radiodurans recA mutants // Scientific reports, 11 (2021), 1; 10939, 11. doi: 10.1038/s41598-021-89173-9
doiwww.nature.comdoi.orgfulir.irb.hr -
Buljubašić, Maja ; Hlevnjak, Ana ; Repar, Jelena ; Đermić, Damir ; Filić, Vedrana ; Weber, Igor ; Zahradka, Ksenija ; Zahradka, Davor | RecBCD- RecFOR-independent pathway of homologous recombination in Escherichia coli // DNA repair, 83 (2019), 102670, 16. doi: 10.1016/j.dnarep.2019.102670
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Feliciello, Isidoro ; Zahradka, Davor ; Zahradka, Ksenija ; Ivanković, Siniša ; Puc, Nikolina ; Đermić, Damir | RecF, UvrD, RecX and RecN proteins suppress DNA degradation at DNA double-strand breaks in Escherichia coli // Biochimie, 148 (2018), 116-126. doi: 10.1016/j.biochi.2018.03.005
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Repar, Jelena ; Supek, Fran ; Klanjšček, Tin ; Warnecke, Tobias ; Zahradka, Ksenija ; Zahradka, Davor | Elevated rate of genome rearrangements in radiation-resistant bacteria // Genetics, 205 (2017), 4; 1677-1689. doi: 10.1534/genetics.116.196154
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Repar, Jelena ; Šućurović, Sandra ; Zahradka, Ksenija ; Zahradka, Davor ; Ćurković-Perica, Mirna | Stress resistance of Escherichia coli and Bacillus subtilis is modulated by auxins // Canadian journal of microbiology, 59 (2013), 11; 766-770. doi: 10.1139/cjm-2013-0266
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Buljubašić, Maja ; Zahradka, Davor ; Zahradka, Ksenija | RecQ helicase acts before RuvABC, RecG and XerC proteins during recombination in recBCD sbcBC mutants of Escherichia coli // Research in microbiology, 164 (2013), 10; 987-997. doi: 10.1016/j.resmic.2013.08.008
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Repar, Jelena ; Zahradka, Davor ; Zahradka, Ksenija | Accuracy of genome reassembly in gamma-irradiated Escherichia coli // Food technology and biotechnology, 51 (2013), 3; 327-337
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Repar, Jelena ; Briški, Nina ; Buljubašić, Maja ; Zahradka, Ksenija ; Zahradka, Davor | Exonuclease VII is involved in "reckless" DNA degradation in UV-irradiated Escherichia coli // Mutation research. Genetic toxicology and environmental mutagenesis, 750 (2013), 1/2; 96-104. doi: 10.1016/j.mrgentox.2012.10.005
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Buljubašić, Maja ; Repar, Jelena ; Zahradka, Ksenija ; Đermić, Damir ; Zahradka, Davor | RecF recombination pathway in Escherichia coli cells lacking RecQ, UvrD and HelD helicases // DNA repair, 11 (2012), 4; 419-430. doi: 10.1016/j.dnarep.2012.01.011
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Repar, Jelena ; Cvjetan, Svjetlana ; Slade, Dea ; Radman, Miroslav ; Zahradka, Davor ; Zahradka, Ksenija | RecA protein assures fidelity of DNA repair and genome stability in Deinococcus radiodurans // DNA repair, 9 (2010), 11; 1151-1161. doi: 10.1016/j.dnarep.2010.08.003
doiwww.sciencedirect.comdoi.org -
Zahradka, Ksenija ; Buljubašić, Maja ; Petranović, Mirjana ; Zahradka, Davor | Roles of ExoI and SbcCD nucleases in "reckless" DNA degradation in recA mutants of Escherichia coli // Journal of bacteriology, 191 (2009), 5; 1677-1687. doi: 10.1128/JB.01877-07
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Petranović, Dina ; Michelsen, Ole ; Zahradka, Ksenija ; Silva, Catarina ; Petranović, Mirjana ; Jensen, Peter Ruhdal ; Mijaković, Ivan | Bacillus subtilis strain deficient for the protein-tyrosine kinase PtkA exhibits impaired DNA replication // Molecular microbiology, 63 (2007), 6; 1797-1805. doi: 10.1111/j.1365-2958.2007.05625.x
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Zahradka, Ksenija ; Slade, Dea ; Bailone, Adriana ; Sommer, Suzanne ; Averbeck, Dietrich ; Petranović, Mirjana ; Lindner, Ariel B. ; Radman, Miroslav | Reassembly of shattered chromosomes in Deinococcus radiodurans // Nature, 443 (2006), 569-573. doi: 10.1038/nature05160
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Zahradka, Ksenija ; Šimić, Sanela ; Buljubašić, Maja ; Petranović, Mirjana ; Đermić, Damir ; Zahradka, Davor | sbcB15 and delsbcB mutations activate two types of RecF recombination pathway in Escherichia coli // Journal of bacteriology, 188 (2006), 21; 7562-7571. doi: 10.1128/JB.00613-06
doijournals.asm.org Zahradka, Ksenija ; Zahradka, Davor ; Đermić, Damir ; Džidić, Senka ; Petranović, Mirjana | The inactivation of free phages in UV-irradiated Escherichia coli // Periodicum biologorum, 104 (2002), 4; 399-403
Zahradka, Davor ; Zahradka, Ksenija ; Džidić, Senka ; Đermić, Damir ; Petranović, Mirjana | The rus-1 mutation suppresses cytological defects in recBC sbcBC ruv mutants of Escherichia coli // Periodicum biologorum, 104 (2002), 4; 389-397-x
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Zahradka, Davor ; Zahradka, Ksenija ; Petranović, Mirjana ; Đermić, Damir ; Brčić-Kostić, Krunoslav | The RuvABC resolvase is indispensable for recombinational repair in sbcB15 mutants of Escherichia coli // Journal of bacteriology, 184 (2002), 15; 4141-4147. doi: 10.1128/JB.184.15.4141-4147.2002
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Petranović, Mirjana ; Zahradka, Ksenija ; Zahradka, Davor ; Petranović, Dina ; Nagy, Biserka ; Salaj-Šmic, Erika ; Petranović, Dragutin | Genetic evidence that the elevated levels of Escherichia coli helicase II antagonize recombinational DNA repair // Biochimie, 83 (2001), 11-12; 1041-1047. doi: 10.1016/S0300-9084(01)01346-3
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Paškvan, Ivan ; Salaj-Šmic, Erika ; Ivančić-Baće, Ivana ; Zahradka, Ksenija ; Trgovčević, Željko ; Brčić-Kostić, Krunoslav | The genetic dependence of RecBCD-Gam mediated double strand end repair in Escherichia coli // FEMS microbiology letters, 205 (2001), 2; 299-303. doi: 10.1111/j.1574-6968.2001.tb10964.x
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Zahradka, Ksenija ; Zahradka, Davor ; Petranović, Mirjana | Loss of lambda prophage recombinogenicity in UV- irradiated Escherichia coli : the role of host genes ruvA, ruvB, ruvC and recG // Research in microbiology, 152 (2001), 10; 873-881. doi: 10.1016/S0923-2508(01)01270-0
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Vlahović, Ksenija ; Petranović, Mirjana ; Zahradka, Davor ; Petranović, Drago | Progressive loss of lambda prophage recombinogenicity in UV-irradiated Escherichia coli : the role of RecBCD enzyme // Research in microbiology, 151 (2000), 9; 727-738. doi: 10.1016/S0923-2508(00)01138-4
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Petranović, Mirjana ; Vlahović, Ksenija ; Zahradka, Davor ; Džidić, Senka ; Radman, Miroslav | Mismatch repair in Xenopus egg extracts is not strand-directed by DNA methylation // Neoplasma, 47 (2000), 6; 375-381
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Zahradka, Davor ; Vlahović, Ksenija ; Petranović, Mirjana ; Petranović, Drago | Chromosome segregation and cell division defects in recBC sbcBC ruvC mutants of Escherichia coli // Journal of bacteriology, 181 (1999), 19; 6179-6183. doi: 10.1128/JB.181.19.6179-6183.1999
doijournals.asm.org Vlahović, Ksenija ; Petranović, Mirjana ; Zahradka, Davor ; Petranović, Dragutin | Effects of ruv and recG mutations on lambda prophage thermoinducibility in UV-irradiated Escherichia coli // Periodicum biologorum, 100 (1998), 3; 383-388-x
Popularni rad
Zahradka, Ksenija | Miroslav Radman - život i djelo // Priroda (Zagreb), 101 (2011), 7/8; 46-49
Publikacije - prilozi sa skupa (u zborniku)
Sažetak izlaganja sa skupa
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Zahradka, Ksenija ; Repar, Jelena ; Đermić, Damir ; Zahradka, Davor | Chromosome segregation and cell division defects in Escherichia coli after induction of double- strand DNA breaks // Power of Microbes in Industry and Environment 2023: Book of Abstracts / Teparić, Renata; Leboš Pavunc, Andreja; Kifer, Domagoj (ur.). | Zagreb: Croatian Microbiological Society, 2023. str. 73-73
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Buljubašić, Maja ; Zahradka, Ksenija ; Hlevnjak, Ana ; Repar, Jelena ; Đermić, Damir ; Zahradka, Davor | RecBCD- RecFOR-independent pathway of homologous recombination in Escherichia coli // 4th Congress of Croatian Geneticists with international participation - Book of Abstracts. | Zagreb: Hrvatsko genetičko društvo, 2018. str. 25-25
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Repar, Jelena ; Supek, Fran ; Klanjscek, Tin ; Warnecke, Tobias ; Zahradka, Ksenija ; Zahradka, Davor | Genome rearrangements in radiation-resistant bacteria // 4th Congress of Croatian Geneticists with international participation : Book of Abstracts. | Zagreb: Hrvatsko genetičko društvo, 2018. str. 24-24
pubweb.carnet.hr Zahradka, Ksenija ; Hlevnjak, Ana ; Repar, Jelena ; Buljubašić, Maja ; Zahradka, Davor | Genetic differences in postsynaptic stages of two recombinational repair pathways in Escherichia coli // EEMGS 2016 Annual Meeting - Programme & Abstract book. | Kopenhagen, 2016. str. 146-146
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Zahradka, Ksenija ; Repar, Jelena ; Buljubašić, Maja ; Zahradka, Davor | ExoI, ExoVII and SbcCD nucleases participate in "reckless" DNA degradation in Escherichia coli // BioMicroWorld 2013 - Book of Abstracts. | 2013. str. 534-534
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Repar, Jelena ; Supek, Fran ; Zahradka, Davor ; Zahradka, Ksenija | Elevated rate of gene order change in radiation-resistant Deinococci // FEMS 2013 - 5th Congress of European Microbiologists. | 2013
www2.kenes.com Buljubašić, Maja ; Repar, Jelena ; Zahradka, Ksenija ; Đermić, Damir ; Zahradka, Davor | Roles of RecQ, UvrD and HelD helicases in the RecF recombination pathway of Escherichia coli // Book of Abstracts of the 3rd Congress of Croatian Geneticists with international participation. | Zagreb: Hrvatsko genetičko društvo, 2012. str. 11-11
Repar, Jelena ; Cvjetan, Svjetlana ; Slade, Dea ; Radman, Miroslav ; Zahradka, Davor ; Zahradka, Ksenija | Fidelity of DNA repair and genome stability in Deinococcus radiodurans // Book of Abstracts of the 3rd Congress of Croatian Geneticists with international participation. | Zagreb: Hrvatsko genetičko društvo, 2012. str. 10-10
Zahradka, Ksenija ; Buljubašić, Maja ; Petranović, Mirjana ; Zahradka, Davor | ExoI and SbcCD nucleases are involved in "reckless" chromosome degradation in recA mutants of Escherichia coli / Nukleaze ExoI i SbcCD sudjeluju u neobuzdanoj razgradnji kromosoma u recA mutantima bakterije Escherichia coli // 10. hrvatski biološki kongres s međunarodnim sudjelovanjem - Zbornik sažetaka. | Zagreb: Hrvatsko biološko društvo, 2009. str. 69-70
Vučemilović, Ante ; Petranović, Mirjana ; Popović Hadžija, Marijana ; Korolija, Marina ; Zahradka, Ksenija ; Hadžija Mirko | Application of 16S ribosomal RNA sequence in the identification of laboratory strains of Bacillus species in the warfare polymer fibre // 4th Croatian Congress of Microbiology with International Participation. | Zadar, 2008
Repar, Jelena ; Cvjetan, Svjetlana ; Zahradka, Davor ; Radman, Miroslav ; Zahradka, Ksenija | Popravak DNA i stabilnost genoma u bakteriji Deinococcus radiodurans // 50 godina molekularne biologije u Hrvatskoj - Zbornik sažetaka. | Zagreb: Institut Ruđer Bošković, 2008. str. 32-32
Buljubašić, Maja ; Zahradka, Ksenija ; Petranović, Mirjana ; Zahradka, Davor | ExoI and SbcCD nucleases cooperate with RecBCD enzyme in reckless chromosome degradation in recA mutants of Escherichia coli // 50 godina molekularne biologije u Hrvatskoj - Zbornik sažetaka. | Zagreb: Institut Ruđer Bošković, 2008. str. 57-57
Zahradka, Ksenija ; Buljubašić, Maja ; Petranović, Mirjana ; Zahradka, Davor | ExoI and SbcCD nucleases cooperate with RecBCD enzyme in reckless chromosome degradation in recA mutants of Escherichia coli // 4th Croatian Congress of Microbiology with International Participation - Programme and Abstracts. | Zagreb: Hrvatsko mikrobiološko društvo, 2008. str. 22-22
Zahradka, Ksenija ; Slade, Dea ; Bailone, Adriana ; Sommer, Suzanne ; Averbeck, Dietrich ; Petranović, Mirjana ; Lindner, Ariel ; Radman, Miroslav | DNA repair in radiation resistant bacterium Deinococcus radiodurans // HDBMB2008 Congress of the Croatian Society of Biochemistry and Molecular Biology With International Participation - Book of Abstracts. | Osijek: Hrvatsko Društvo za Biotehnologiju, 2008. str. 44-44
Zahradka, Ksenija | Survival of Deinococcus radiodurans in extreme environments // MedILS Summer School 2008 "Life in Extreme Conditions". | 2008
Zahradka, Ksenija ; Slade, Dea ; Bailone, Adriana ; Sommer, Suzanne ; Averbeck, Dietrich ; Petranovic, Mirjana ; Lindner, Ariel ; Radman, Miroslav | Survival of Deinococcus radiodurans in extreme conditions: genome restoration by recombination // Power of microbes in industry and environment 2007 - Central European Symposium on Industrial Microbiology and Microbial Ecology. | Zagreb: Hrvatsko mikrobiološko društvo, 2007. str. 23-23-x
Zahradka, Ksenija | DNA repair in Deinococcus radiodurans: surviving extreme life conditions // MedILS Summer School 2007 "Survivng death - an interdisciplinary approach workshop". | 2007
Zahradka, Ksenija ; Slade, Dea ; Bailone, Adriana ; Sommer, Suzanne ; Averbeck, Dietrich ; Petranović, Mirjana ; Lindner, Ariel ; Radman, Miroslav | DNA repair in Deinococcus radiodurans: from hundreds of fragments to the functional chromosomes // Current Trends in Biomedicine Workshop: Mechanism and biological consequences of recombinational DNA repair-mediated genome instability. | Baeza, 2006
Buljubašić, Maja ; Zahradka, Ksenija ; Petranović, Mirjana ; Zahradka, Davor | Effects of a recG mutation on homologous recombination and DNA repair in recBC sbcBC mutants of Escherichia coli // 1st MedILS Summer School, Structure and Evolution: from Bench to Terminal (Abstract Book). | 2006. str. 25-25-x
Zahradka, Davor ; Zahradka, Ksenija ; Buljubašić, Maja ; Petranović, Mirjana | The role of SbcB and SbcCD nucleases in spontaneous DNA degradation in recA mutants of Escherichia coli // Zbornik sažetaka 9. hrvatskog biološkog kongresa s međunarodnim sudjelovanjem. | Zagreb: Hrvatsko biološko društvo, 2006. str. 84-85-x
Buljubašić, Maja ; Zahradka, Ksenija ; Petranović, Mirjana ; Zahradka, Davor | Effects of a recG mutation on homologous recombination and DNA repair in recBC sbcBC mutants of Escherichia coli // Zbornik sažetaka 9. hrvatskog biološkog kongresa s međunarodnim sudjelovanjem. | Zagreb: Hrvatsko biološko društvo, 2006. str. 71-73-x
Zahradka, Ksenija ; Radman, Miroslav | DNA repair in Deinococcus radiodurans: from hundreds of fragments to the functional chromosome // Zbornik sažetaka 9. hrvatskog biološkog kongresa s međunarodnim sudjelovanjem. | Zagreb: Hrvatsko biološko društvo, 2006. str. 59-60-x
Zahradka, Davor ; Buljubašić, Maja ; Zahradka, Ksenija ; Petranović, Mirjana | Effects of a recG Mutation on Homologous Recombination and Recombinational DNA Repair in recBC sbcBC Mutants of Escherichia coli // Book of Abstracts. Second Congress of Croatian Geneticists with International Participation. | Zagreb: Hrvatsko genetičko društvo, 2005. str. 84-84-x
Zahradka, Ksenija ; Bailone, Adriana ; Averbeck, Dietrich ; Petranović, Mirjana ; Radman, Miroslav | Reconstitution of Deinococcus radiodurans Chromosomes Shattered by Radiation Involves DNA Replication and Recombination // Book of Abstracts. Second Congress of Croatian Geneticists. | Zagreb: Hrvatsko genetičko društvo, 2005. str. 55-55-x
Zahradka, Davor ; Zahradka, Ksenija ; Petranović, Mirjana | Cytological defects in recBC sbcBC ruv mutants of Escherichia coli // Zbornik = Proceedings / Treći hrvatski mikrobiološki kongres s međunarodnim sudjelovanjem, Poreč, 4.-7. listopada 2004.. | Zagreb: Hrvatsko mikrobiološko društvo, 2004. str. 88-88-x
Zahradka, Ksenija ; Bailone, Adriana ; Averbeck, Dietrich ; Radman, Miroslav | Reconstitution of Deinococcus radiodurans genome after gamma irradiation // Zbornik = Proceedings / Treći hrvatski mikrobiološki kongres s međunarodnim sudjelovanjem, Poreč, 4.-7. listopada 2004.. | Zagreb: Hrvatsko mikrobiološko društvo, 2004. str. 45-45-x
Zahradka, Davor ; Zahradka, Ksenija ; Petranović, Mirjana | Suppression of cytological defects in recBC sbcBC ruv mutants of Escherichia coli // EMBO Conference on Molecular Microbiology: Exploring Prokaryotic Diversity - Abstract Book. | Heidelberg: EMBL, 2004. str. 127-127-x
Zahradka, Ksenija ; Bailone, Adriana ; Averbeck, Dietrich ; Radman, Miroslav | The mechanism of DNA repair in radioresistant bacterium Deinococcus radiodurans // 2nd Scientific Symposium with International Participation "45 Years of Molecular Biology in Croatia 50 Years of Double Helix", Book of Abstracts. | Zagreb: Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu, 2003. str. 25-25-x
Zahradka, Davor ; Zahradka, Ksenija ; Đermić, Damir ; Brčić-Kostić, Krunoslav ; Petranović, Mirjana | The RuvABC resolvase is indispensable for recombinational repair in sbcB15 mutants of Escherichia coli // 2nd Scientific Symposium with International Participation "45 Years of Molecular Biology in Croatia 50 Years of Double Helix", Book of Abstracts. | Zagreb: Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu, 2003. str. 24-25-x
Petranović, Dina ; Džidić, Senka ; Zahradka, Davor ; Zahradka, Ksenija ; Petranović, Mirjana | Activation and inhibition of lambda phage multiplicity reactivation // 2nd Scientific Symposium with International Participation "45 Years of Molecular Biology in Croatia 50 Years of Double Helix", Book of Abstracts. | Zagreb: Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu, 2003. str. 23-23-x
Zahradka, Ksenija ; Bailone, Adriana ; Averbeck, Dietrich ; Radman, Miroslav | Mechanism of DNA repair in radioresistant bacterium Deinococcus radiodurans // Proceedings of Abstracts of the 8th Croatian Biological Congress. | Zagreb: Hrvatsko biološko društvo, 2003. str. 47-48-x
Petranović, Dina ; Zahradka, Ksenija ; Zahradka, Davor ; Džidić, Senka ; Petranović, Mirjana | Genetic analysis of multiplicity reactivation of UV-irradiated lambda phage // Proceedings of Abstracts of the 8th Croatian Biological Congress. | Zagreb: Hrvatsko biološko društvo, 2003. str. 45-46-x
Paškvan, Ivan ; Salaj-Šmic, Erika ; Ivančić-Baće, Ivana ; Zahradka, Ksenija ; Lerš, Nella ; Brčić-Kostić, Krunoslav | The genetic depedence of RecBCD-Gam mediated double strand end repair in Escherichia coli // 1st Croatian Congress on Molecular Life Sciences with international participation, Book of Abstracts. | Zagreb: Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu, 2002. str. 95-x
Petranović, Mirjana ; Vlahović, Ksenija ; Zahradka, Davor ; Salaj-Šmic, Erika ; Petranović, Drago | Genetics of antirecombination in SOS-induced Escherichia coli // Quatrieme Colloque des 3R (Replication, recombinaison, reparation). | Pariz: INRA, 2001. str. 53-53-x
Vlahović, Ksenija ; Zahradka, Davor ; Petranović, Mirjana | RecBCD enzyme in UV-irradiated Escherichia coli interferes with site-specific and general recombination of lambda prophage // Kongres hrvatskih biokemičara i molekularnih biologa HB2000 - Knjiga sažetaka. | Zagreb: Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu, 2000. str. 69-69-x
Vlahović, Ksenija ; Zahradka, Davor ; Petranović, Mirjana ; Petranović, Drago | Effects of UV radiation on genetic recombination // Zbornik radova Trećeg simpozija Hrvatskoga društva za zaštitu od zračenja / Proceedings of the Third Symposium of the Croatian Radiation Protection Association. | Zagreb: Hrvatsko društvo za zaštitu od zračenja, 1996. str. 161-161
Vlahović, Ksenija ; Petranović, Mirjana ; Zahradka, Davor ; Petranović, Dragutin | Enzim RecBC(D) inhibira rekombinaciju profaga lambda u ozračenim stanicama Escherichia coli = RecBC(D) enzyme inhibits recombination of lambda prophage in irradiated Escherichia coli cells // Zbornik sažetaka priopćenja Šestog kongresa biologa Hrvatske = Proceedings of abstracts of the papers of the Sixth Congress of Croatian Biologists. | Zagreb: Hrvatsko biološko društvo, 1997. str. 74-75-x
Zahradka, Davor ; Vlahović, Ksenija ; Petranović, Mirjana ; Ljubešić, Nikola ; Petranović, Dragutin | Inhibicija diobe stanica Escherichia coli izazvana UV zračenjem = UV-induced division inhibition in Escherichia coli // Zbornik sažetaka priopćenja Šestog kongresa biologa Hrvatske = Proceedings of abstracts of the papers of the Sixth Congress of Croatian Biologists. | Zagreb: Hrvatsko biološko društvo, 1997. str. 75-76-x
Petranović, Dragutin ; Vlahović, Ksenija ; Zahradka, Davor ; Džidić, Senka ; Petranović, Mirjana | Antirekombinaze u stanicama Escherichia coli = Antirecombinases in Escherichia coli cells // Zbornik sažetaka priopćenja Šestog kongresa biologa Hrvatske = Proceedings of abstracts of the papers of the Sixth Congress of Croatian Biologists. | Zagreb: Hrvatsko biološko društvo, 1997. str. 68-x
Petranović, Dragutin ; Petranović, Mirjana ; Vlahović, Ksenija ; Zahradka, Davor | Genetics of anti-recombination in SOS-induced Escherichia coli // ICGEB 10 th Anniversary Symposium: Molecular Biology and Biotechnology for Development. | ICGEB, 1997. str. 31-32-x
Izvorni znanstveni rad
Zahradka, Ksenija | Deinococcus radiodurans : bakterija otporna na zračenje // Zbornik radova Sedmog simpozija Hrvatskog društva za zaštitu od zračenja. | Zagreb: Hrvatsko društvo za zaštitu od zračenja, 2008. str. 3-8
Publikacije - prilozi sa skupa (u časopisu)
Sažetak izlaganja sa skupa
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Repar, Jelena; Zahradka, Davor; Zahradka, Ksenija | DNA double-strand break repair and genome stability in the bacterium Deinococcus radiodurans // Arhiv za higijenu rada i toksikologiju, 75, Suppl. 1, 2024. str. 27-27
hrcak.srce.hr -
Repar, Jelena; Zahradka, Davor; Zahradka, Ksenija | New evidence for an alternative end-joining mechanism of DNA double-strand break repair in Deinococcus radiodurans // Arhiv za higijenu rada i toksikologiju, 75, Suppl. 1, 2024. str. 194-194
hrcak.srce.hr Zahradka, Ksenija ; Bailone, Adriana ; Averbeck, Dietrich ; Petranović, Mirjana ; Radman, Miroslav | Deinococcus radiodurans: The Most Efficient DNA Repair Involves Coupled Replication and Recombination Processes // Acta microbiologica et immunologica Hungarica, 2005. str. 175-175
Zahradka, Davor ; Buljubašić, Maja ; Zahradka, Ksenija ; Petranović, Mirjana | Homologous Recombination and DNA Repair in recBC sbcBC Mutants of Escherichia coli: Effects of a recG Mutation // Acta microbiologica et immunologica Hungarica, 2005. str. 174-175
Zahradka, Davor ; Vlahović, Ksenija ; Petranović, Mirjana ; Petranović, Drago | Chromosome segregation and cell morphology in recBC sbcBC ruvC mutants of Escherichia coli // Biochimie, 1999. str. s280-x
Vlahović, Ksenija ; Petranović, Mirjana ; Zahradka, Davor ; Petranović, Drago | RecBC(D) enzyme in UV-irradiated E. coli interferes with lambda prophage recombinogenicity // Biochimie, 1999. str. s280-x
Petranović, Mirjana ; Zahradka, Davor ; Vlahović, Ksenija ; Petranović, Dragutin | Genetic analysis of the multiplicity reactivation of UV-inactivated lambda red phage // Periodicum biologorum. Supplement, 1998. str. 39-39
Vlahović, Ksenija ; Petranović, Mirjana ; Zahradka, Davor ; Petranović, Dragutin | Recombination and antirecombination in UV-irradiated Escherichia coli: the role of ruvB, ruvC, and recG genes // Periodicum biologorum. Supplement, 1998. str. 39-39
Petranović, Mirjana ; Vlahović, Ksenija ; Zahradka, Davor ; Petranović, Dragutin | RecBC(D) enzyme in UV-irradiated E. coli interferes with site-specific and general recombination of lambda prophage // FASEB journal, 1997. str. A1194-x
Publikacije - prilozi sa skupa (neobjavljeni)
Neobjavljeni prilog sa skupa
Pipalović, Goran ; Filić, Želimira ; Ćehić, Mirsada ; Paradžik, Tina ; Crnolatac, Ivo ; Zahradka, Ksenija ; Vujaklija, Dušica | Possible role of SSB protein in the regulation of antibiotic production // Summer school in applied molecular microbiology on microbial specialised metabolites | Dubrovnik, Hrvatska, 10.09.2022-17.09.2022
Repar, Jelena ; Supek, Fran ; Zahradka, Davor ; Zahradka, Ksenija | Environmentally induced increase of rearrangement rates in radiation resistant prokaryotes // SMBE 2015 - annual meeting of the Society for Molecular Biology and Evolution | Beč, Austrija, 12.07.2015-16.07.2015
Zahradka, Ksenija ; Buljubašić, Maja ; Petranović, Mirjana ; Zahradka, Davor | The role of ExoI and SbcCD nucleases in spontaneous DNA degradation in Escherichia coli recA mutants // Second John Innes-Rudjer Bošković summer school in Applied Molecular Microbiology "Microbial Secondary Metabolites: Genomes, Signals and Communities" | Dubrovnik, Hrvatska, 24.08.2008-01.09.2008
Publikacije - ocjenski radovi
Doktorska disertacija
Cvjetan, Svjetlana | Kromosomski rearanžmani u ozračenim mrtvim stanicama bakterije Deinococcus radiodurans: uloga insercijskih sekvenci i proteina RecA / Zahradka, Ksenija ; Radman, Miroslav (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2013
Repar, Jelena | Točnost popravka DNA u stanicama bakterije Deinococcus radiodurans nakon gama-zračenja / Zahradka, Ksenija (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2012
Vlahović, Ksenija | Genetička analiza rekombinogenosti profaga lambda u ozračenim bakterijama Escherichia coli / Petranović, Mirjana (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 1999
Diplomski rad
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Hleb, Ana | Genomski rearanžmani u bakteriji Deinococcus radiodurans: uloga proteina RecG / Hulak, Nataša ; Zahradka, Ksenija (mentor). | Zagreb, Agronomski fakultet, 2018
urn.nsk.hr Dobša, Lidija | Popravak DNA u stacionarnim stanicama bakterije Deinococcus radiodurans / Zahradka, Ksenija (mentor). | Zagreb, Farmaceutsko-biokemijski fakultet, 2010
Vukić, Marijana | Genetička nestabilnost recA mutanata bakterije Deinococcus radiodurans / Zahradka, Ksenija (mentor). | Zagreb, Farmaceutsko-biokemijski fakultet, 2010
Šimić, Sanela | Učinak mutacija sbcB15 i delsbcB na rekombinacijski popravak molekule DNA kod recBC mutanata bakterije Escherichia coli / Zahradka, Ksenija (mentor). | Zagreb, Farmaceutsko-biokemijski fakultet, 2006
Publikacije - druge vrste radova
Radovi sa studija
Dobša, Lidija ; voditelj Zahradka, Ksenija | Otpornost na zračenje stacionarnih stanica bakterije Deinococcus radiodurans // Otpornost na zračenje stacionarnih stanica bakterije Deinococcus radiodurans, Sveučilište u Zagrebu, Farmaceutsko-biokemijski fakultet, 2008
Članstva u profesionalnim udrugama / društvima
- European Environmental Mutagenesis and Genomics Society (EEMGS): 2015-2019 hrvatski delegat
- Hrvatsko genetičko društvo: 2019-2022 tajnica; od 2022. dopredsjednica
- Hrvatsko mikrobiološko društvo
- Hrvatsko društvo za biokemiju i molekularnu biologiju
- predsjednica Zakladnog vijeća programa "Znanje i otkrića" Zaklade Adris (od 2015.)
- članica Znanstvenog vijeća Mediteranskog instituta za istraživanje života (2015-2022)
- zamjenica predsjednice Znanstvenog vijeća struke-biologija IRB-a (2016-2022)
Organizacija znanstvenih skupova::
- 52nd European Environmental Mutagenesis and Genomics Society Meeting & 15th International Comet Assay Workshop, Rovinj, 2024. - članica Organizacijskog i Znanstvenog odbora
- 4th Congress of Croatian Geneticists with international participation, Krk, 2018. – članica Znanstvenog odbora
- 3rd Congress of Croatian Geneticists with international participation, Krk, 2012. – članica Znanstvenog odbora
- "Power of Microbes in Industry and Environment 2010" - Central European Symposium on Industrial Microbiology and Microbial Ecology, Malinska, 2010. - članica Organizacijskog odbora
- 10th International Summer School in Biophysics "Supramolecular Structure and Function", Rovinj, 2009. - članica Organizacijskog odbora i urednica Knjige sažetaka
- 10th Croatian Biological Congress with international participation, Osijek, 2009. – članica Znanstvenog i Organizacijskog odbora
- Znanstveni simpozij "50 godina molekularne biologije u Hrvatskoj", Zagreb, 2008. - predsjednica Organizacijskog odbora i urednica Knjige sažetaka
- 9th Croatian Biological Congress with international participation, Rovinj, 2006. –članica Znanstvenog odbora
- Znanstveni simpozij "45 godina molekularne biologije u Hrvatskoj i 50 godina dvostruke uzvojnice DNA", Zagreb, 2003. - članica Organizacijskog odbora
Patent: PCT/EP2006/005826 (10/05/2006) "Process for chromosomal engineering using a novel DNA repair system", inventori: M. Radman, K. Zahradka.