dr. sc. Nikolina Piteša
10002 Zagreb
Obrazovanje
2020-2023: Sveučilište Josipa Jurja Strossmayera Osijek, Institut Ruđer Bošković Zagreb, Sveučilište Dubrovnik, Poslijediplomski interdisciplinarni sveučilišni studij Molekularne bioznanosti
2016-2018: Sveučilište u Zagrebu, Prirodoslovno-matematički fakultet, Biološki odsjek, Diplomski studij eksperimentalne biologije
2013-2016: Sveučilište u Zagrebu, Prirodoslovno-matematički fakultet, Biološki odsjek, Preddiplomski studij znanosti o okolišu
Projekti
asistent/doktorand u sklopu projekta ''2019-2022 HRZZ IP-01-2018-4889 "Regulacija GLI koda u tumorima ovisnim o BRAF/NRAS mutacijama"
Nastava
Asistent u nastavi kolegija "Biologija tumorskih i normalnim stanica" za poslijediplomski interdisciplinarni sveučilišni studij Molekularne bioznanosti Sveučilišta Josipa Jurja Strossmayera Osijek, Institut Ruđer Bošković Zagreb, Sveučilište Dubrovnik
Asistent u nastavi kolegija "Metode istraživanja u molekularnoj onkologiji" za poslijediplomski studij Biomedicina i zdravstvo, Medicinski fakultet Sveučilišta u Zagrebu
Istaknute publikacije
Trnski D, Gregorić M, Levanat S, Ozretić P, Rinčić N, Majić Vidaković T, Kalafatić D, Maurac I, Orešković S, Sabol M, Musani V. Regulation of Survivin isoform expression by GLI proteins in ovarian cancer. Cells, 8 (2019) 128.
Publikacije - prilozi u časopisima
Izvorni znanstveni rad
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Kurtović, Matea; Piteša, Nikolina; Čonkaš, Josipa; Hajpek, Helena; Vučić, Majda; Musani, Vesna; Ozretić, Petar; Sabol, Maja | GLI transcriptional targets S100A7 and KRT16 show upregulated expression patterns in epidermis overlying the tumor mass in melanoma samples // International journal of molecular sciences, 25 (2024), 11; 6084, 19. doi: 10.3390/ijms25116084
doiwww.mdpi.comfulir.irb.hr Car, Iris; Dittmann, Antje; Vasieva, Olga; Bočkor, Luka; Grbčić, Petra; Piteša, Nikolina; Klobučar, Marko; Kraljević Pavelić, Sandra; Sedić, Mirela | Ezrin inhibition overcomes acquired resistance to vemurafenib in BRAFV600E-mutated colon cancer and melanoma cells in vitro // International journal of molecular sciences, 2023 (2023), 24; 12906-12931
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Piteša, Nikolina ; Kurtović, Matea ; Bartoniček, Nenad ; Gkotsi, Danai S ; Čonkaš, Josipa ; Petrić, Tina ; Musani, Vesna ; Ozretić, Petar ; Riobo-Del Galdo, Natalia ; Sabol, Maja | Signaling switching from Hedgehog-GLI to MAPK signaling potentially serves as a compensatory mechanism in melanoma cell lines resistant to GANT-61 // Biomedicines, 11 (2023), 1353, 19. doi: 10.3390/biomedicines11051353
doiwww.mdpi.comfulir.irb.hr -
Kurtović, Matea ; Piteša, Nikolina ; Bartoniček, Nenad ; Ozretić, Petar ; Musani, Vesna ; Čonkaš, Josipa ; Petrić, Tina ; King, Cecile ; Sabol, Maja | RNA-seq and ChIP-seq Identification of Unique and Overlapping Targets of GLI Transcription Factors in Melanoma Cell Lines // Cancers, 14 (2022), 18; 4540, 20. doi: 10.3390/cancers14184540
doiwww.mdpi.comwww.ncbi.nlm.nih.govfulir.irb.hr -
Trnski, Diana ; Sabol, Maja ; Tomić, Sanja ; Štefanac, Ivan ; Mrčela, Milanka ; Musani, Vesna ; Rinčić, Nikolina ; Kurtović, Matea ; Petrić, Tina ; Levanat, Sonja et al. | SHH-N non-canonically sustains androgen receptor activity in androgen-independent prostate cancer cells // Scientific reports, 11 (2021), 1; 14880, 11. doi: 10.1038/s41598-021-93971-6
doiwww.nature.comdoi.orgfulir.irb.hr -
Zubčić, Vedran ; Rinčić, Nikolina ; Kurtović, Matea ; Trnski, Diana ; Musani, Vesna ; Ozretić, Petar ; Levanat, Sonja ; Leović, Dinko ; Sabol, Maja | GANT61 and Lithium Chloride Inhibit the Growth of Head and Neck Cancer Cell Lines Through the Regulation of GLI3 Processing by GSK3beta // International journal of molecular sciences, 21 (2020), 6410, 13. doi: 10.3390/ijms21176410
doiwww.mdpi.comfulir.irb.hr -
Trnski, Diana ; Gregorić, Maja ; Levanat, Sonja ; Ozretić, Petar ; Rinčić, Nikolina ; Majić Vidaković, Tajana ; kalafatić, Držislav ; Maurac, Ivana ; Orešković, Slavko ; Sabol, Maja et al. | Regulation of Survivin Isoform Expression by GLI Proteins in Ovarian Cancer // Cells, 8 (2019), 2; 128, 13. doi: 10.3390/cells8020128
doiwww.mdpi.comdoi.orgfulir.irb.hr
Pregledni rad (znanstveni)
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Lučić, Ivan; Kurtović, Matea; Mlinarić, Monika; Piteša, Nikolina; Čipak Gašparović, Ana; Sabol, Maja; Milković, Lidija | Deciphering Common Traits of Breast and Ovarian Cancer Stem Cells and Possible Therapeutic Approaches // International journal of molecular sciences, 24 (2023), 13; 10683, 43. doi: 10.3390/ijms241310683
doi
Publikacije - prilozi sa skupa (u zborniku)
Sažetak izlaganja sa skupa
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Vučemilo Paripović, Nikolina; Piteša, Nikolina; Kurtović Kodžoman, Matea; Petrić, Tina; Sabol, Maja | Establishing a Three-Dimensional Spheroid Culture of Head and Neck Tumor Cells // HDIR-7: Advances in Cancer Research and Treatment: Book of Abstracts / Ozretić, Petar (ur.). | Zagreb: Hrvatsko društvo za istraživanje raka (HDIR), 2024. str. 58-58
stari.hdir.hr Kurtović, Matea ; Bartoniček, Nenad ; Piteša, Nikolina ; Ozretić, Petar ; Musani, Vesna ; Čonkaš, Josipa ; Sabol, Maja | Unique and overlapping transcriptional targets of GLI1, GLI2 and GLI3 in melanoma cell lines. | 2023. str. 66-66
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Piteša, Nikolina ; Kurtović, Matea ; Bartoniček, Nenad ; Gkotsi, Danai S, Čonkaš, Josipa ; Petrić, Tina ; Musani, Vesna ; Ozretić, Petar ; Riobo-Del Galdo, Natalia A ; Sabol, Maja | First Insights into the Characterization of GANT61 - Resistant Melanoma Cell Lines // Hedgehog signaling: From molecular structure to dveelopmental biology and diseases : Abstract book. | 2023. str. 76-76
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Čonkaš, Josipa ; Josić, Janja ; Kranjčević, Jacqueline-Katrin ; Piteša, Nikolina ; Kurtović, Matea ; Musani, Vesna ; Sabol, Maja ; Vugrinec, Ozren ; Mumlek, Ivan ; Kvolik Pavić, Ana et al. | Correlation between the sex hormone receptors expression and demographic parameters in HNSCC patients // 7th Faculty of Science PhD Student Symposium : Book of Abstracts. | Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2023. str. 88-88
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Kurtović, Matea ; Piteša, Nikolina ; Bartoniček, Nenad ; Ozretić, Petar ; Musani, Vesna ; Petrić, Tina ; Čonkaš, Josipa ; Sabol, Maja | Unique and overlapping transcriptional targets of GLI1, GLI2 and GLI3 in melanoma cell lines // “HDIR-6: Targeting Cancer” The 6th Meeting of the Croatian Association for Cancer Research with International Participation / Ozretić, Petar - Zagreb : Croatian Association for Cancer Research, 2022. | 2022. str. 25-25
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Petrić, Tina ; Kurtović, Matea ; Piteša, Nikolina ; Čonkaš, Josipa ; Musani, Vesna ; Ozretić, Petar ; Sabol, Maja | 3D culture of prostate cancer as a model to study hedgehog-gli signaling pathway // “HDIR-6: Targeting Cancer” The 6th Meeting of the Croatian Association for Cancer Research with International Participation : Book of Abstracts. | Zagreb: Hrvatsko društvo za istraživanje raka (HDIR), 2022. str. 44-44
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Petrić, Tina ; Kurtović, Matea ; Piteša, Nikolina ; Čonkaš, Josipa ; Musani, Vesna ; Ozretić, Petar ; Sabol, Maja | Hedgehog-GLI signaling pathway in 3D model of prostate cancer // From Science to Knowledge. | Zagreb: Hrvatsko društvo za biokemiju i molekularnu biologiju (HDBMB), 2022. str. 117-117
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Piteša, Nikolina ; Bartoniček, Nenad ; Kurtović, Matea ; Petrić, Tina ; Čonkaš, Josipa ; Musani, Vesna ; Ozretić, Petar ; Sabol, Maja | Signaling Switch from Hedgehog-GLI to MAPK Potentially Drives Primary Cilia Loss in NRAS Mutated GANT61-Resistant Melanoma Cell Line // “HDIR-6: Targeting Cancer” - The 6th Meeting of the Croatian Association for Cancer Research with International Participation : Book of Abstracts. | Zagreb: Hrvatsko društvo za istraživanje raka (HDIR), 2022. str. 45-45
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Čonkaš, Josipa ; Josić, Janja ; Piteša, Nikolina ; Kurtović, Matea ; Petrić, Tina ; Musani, Vesna ; Sabol, Maja ; Vugrinec, Ozren ; Leović, Dinko ; Ozretić, Petar | Membrane androgen receptor OXER1 indicates a potential role in metastasis of head and neck tumors // “HDIR-6: Targeting Cancer” - The 6th Meeting of the Croatian Association for Cancer Research with International Participation : Book of Abstracts. | Zagreb: Hrvatsko društvo za istraživanje raka (HDIR), 2022. str. 36-36
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Piteša, Nikolina ; Bartoniček, Nenad ; Kurtović, Matea ; Petrić, Tina ; Čonkaš, Josipa ; Musani, Vesna ; Ozretić, Petar ; Sabol, Maja | Primary cilia - a potential link between hedgehog- GLI and MAPK signaling in GANT61 -resistant melanoma cell lines // Book of Abstracts of the Congress of the Croatian Society of Biochemistry and Molecular Biology HDBMB22: From Science to Knowledge. | Zagreb: Hrvatsko društvo za biokemiju i molekularnu biologiju (HDBMB), 2022. str. 119-119
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Kurtović, Matea ; Bartoniček, Nenad ; Piteša, Nikolina ; Ozretić, Petar ; Musani, Vesna ; Petrić, Tina ; Čonkaš, Josipa ; Sabol, Maja | RNA sequencing reveals unique and overlapping transcriptional targets of GLI1, GLI2 and GLI3 in melanoma cell lines // EACR 2022 Congress Abstracts. | 2022, P1-235, 1
www.eacr.org Piteša, N ; Kurtović, M ; Bartoniček, N ; Petrić, T ; Čonkaš, J ; Musani, V ; Ozretić, P ; Sabol, M | Hedgehog-GLI and MAPK signalling pathway activity in GANT61-resistant melanoma cells // Online abstracts. | 2022, EACR22-0296, 1
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Čonkaš, Josipa ; Josić, Janja ; Piteša, Nikolina ; Kurtović, Matea ; Petrić, Tina ; Musani, Vesna ; Sabol, Maja ; Vugrinec, Ozren ; Leović, Dinko ; Ozretić, Petar | The role of androgen and androgen receptors in metastasis of head and neck tumors // 6. simpozij studenata doktorskih studija PMF-a : knjiga sažetaka = 6th Faculty of Science PhD student symposium : book of abstracts. | Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2022. str. 192-193
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Piteša, Nikolina ; Bartoniček, Nenad ; Kurtović, Matea ; Musani, Vesna ; Trnski, Diana ; Ozretić, Petar ; Sabol, Maja | Genes for competing endogenous RNAs as targets of transcription factors GLI in melanoma cell lines // Serbian Association for Cancer Research-5th Congress of SDIR: Translational Potential of Cancer Research in Serbia (Abstract book). | Beograd: Srpsko društvo istraživača raka, 2021. str. 9-9
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Kurtović, Matea ; Rinčić, Nikolina ; Trnski, Diana ; Musani, Vesna ; Ozretić, Petar ; Sabol, Maja | CRISPR/Cas9 mediated knockout of GLI1, GLI2 and GLI3 genes in melanoma cell lines // 45th FEBS Congress Abstracts. | 2021, 38528, 1
2021.febscongress.org -
Kurtović, Matea ; Rinčić, Nikolina ; Trnski, Diana ; Musani, Vesna ; Ozretić, Petar ; Sabol, Maja | CRISPR/Cas9 mediated knockout of GLI1, GLI2 and GLI3 genes in melanoma cell lines. | 2021, 38528, 1
2021.febscongress.org Kurtović, Matea ; Rinčić, Nikolina ; , Trnski, Diana ; Musani, Vesna ; Ozretić, Petar ; Sabol, Maja | Generation of GLI1, GLI2 and GLI3 knock-out melanoma cell lines via CRISPR/Cas9 gene editing. | 2021, EACR21v 0165, 1
Ozretić, Petar ; Trnski, Diana ; Sabol, Maja ; Musani, Vesna ; Rinčić, Nikolina ; Kalafatić, Držislav ; Bodetić, Dejan ; Plattner, Christina ; Hackl, Hubert ; Zeilinger, Robert et al. | Downregulation of Hedgehog-GLI signaling pathway genes by miRNA molecules in high-grade serous ovarian carcinoma // PROGRAM AND ABSTRACTS - The Eleventh ISABS Conference on Forensic and Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine. | Zagreb: International Society for Applied Biological Sciences (ISABS), 2019. str. 150-150
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Rinčić, Nikolina ; Sabol, Maja ; Trnski, Diana ; Musani, Vesna ; Ozretić, Petar ; Gregorić, Maja ; Levanat, Sonja | Uloga proteina GLI u karcinogenezi jajnika // Simpozij „Prvih 10 godina HDIR-a“ – knjiga sažetaka. | Zagreb: Hrvatsko društvo za istraživanje raka (HDIR), 2019. str. 17-17
hdir.hr Trnski, Diana ; Sabol, Maja ; Ozretić, Petar ; Musani, Vesna ; Rinčić, Nikolina ; Štefanac, Ivan ; Mrčela, Milanka ; Levanat, Sonja | Hedgehog signaling in prostate cancer androgen (in)dependence // HDBMB2019 Crossroads in Life Sciences. | Zagreb: Hrvatsko Društvo za Biotehnologiju, 2019. str. 131-131
Križanac, Marinela ; Leović, Matko ; Rinčić, Nikolina ; Trnski, Diana ; Musani, Vesna ; Ozretić, Petar ; Levanat, Sonja ; Zubčić, Vedran ; Leović, Dinko ; Sabol, Maja | Hedgehog-GLI signaling controls proliferation and invasiveness of head and neck squamous cell carcinoma // HDBMB2019 Crossroads in Life Sciences. | Zagreb: Hrvatsko Društvo za Biotehnologiju, 2019. str. 115-115
Publikacije - prilozi sa skupa (u časopisu)
Sažetak izlaganja sa skupa
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Čonkaš, Josipa; Josić, Janja; Kranjčević, Jacqueline-Katrin; Milutin Gašperov, Nina; Piteša, Nikolina; Kurtović, Matea; Musani, Vesna; Sabol, Maja; Vugrinec, Ozren; Mumlek, Ivan et al. | Expression Profile of Sex Hormone Receptors in Head and Neck Cancer: Unraveling Gender Disparities // Oncology insights, 1, 1, 2023. str. 88-89
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Gregorić, Maja ; Trnski, Diana ; Sabol, Maja ; Ozretić, Petar ; Levanat, Sonja ; Rinčić, Nikolina ; Kalafatić, Držislav ; Musani, Vesna | Survivin isoform expresion in GLI1-3 knock-out ovarian carcinoma cell lines // Libri oncologici : Croatian journal of oncology, 2018. str. 65-65
hrcak.srce.hr -
Rinčić, Nikolina ; Sabol, Maja ; Trnski, Diana ; Musani, Vesna ; Ozretić, Petar ; Levanat, Sonja | Responsiveness to GANT-61 inhibitor of GLI1, GLI2 and GLI3 knock-out ovarian cancer cell lines // Libri oncologici : Croatian journal of oncology, 2018. str. 81-81
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Sabol, Maja ; Rinčić, Nikolina ; Trnski, Diana ; Musani, Vesna ; Ozretić, Petar ; Levanat, Sonja | Generation of the GLI1, GLI2 and GLI3 knock-out ovarian cancer cell lines using the CRISPR/Cas9 // ESMO Open, 2018. str. A300-A300. doi: 10.1136/esmoopen-2018-EACR25.707
doiwww.eacr25.org
Prošireni sažetak izlaganja sa skupa
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Piteša, Nikolina; Kurtović, Matea; Čonkaš, Josipa; Musani, Vesna; Ozretić, Petar; Sabol, Maja | The role of Hedgehog signaling pathway in plasticity, stemness and resistance of melanoma // Oncology insights, 1, 1, 2023. str. 47-48
www.sdir.ac.rs
Publikacije - prilozi sa skupa (neobjavljeni)
Neobjavljeni prilog sa skupa
Piteša, Nikolina ; Bartoniček, Nenad ; Kurtović, Matea ; Petrić, Tina ; Čonkaš, Josipa ; Musani, Vesna ; Ozretić, Petar ; Sabol, Maja | Characterization of GANT61 Resistant Cell Lines reveals new insights of Hedgehog-GLI and RAS/RAF/MAPK interplay in melanoma // EACR-Boehringer Ingelheim Drugging and Regulating the MAP Kinase Pathway | online event, 21.02.2023-22.02.2023
Rinčić, Nikolina ; Bartoniček, Nenad ; Kurtović, Matea ; Musani, Vesna ; Trnski, Diana ; Ozretić, Petar ; Sabol, Maja | Specific and overlapping GLI transcription targets in melanoma // EACR 2021 : : Innovative Cancer Science | online, 09.06.2021-12.06.2021
Rinčić, Nikolina ; Nenad, Bartoniček ; Matea, Kurtović ; Vesna, Musani ; Diana, Trnski ; Petar, Ozretić ; Maja, Sabol | GLI transcription targets in melanoma cell lines // 45th FEBS Virtual Congress “Molecules of Life: Towards New Horizons“ | online, 03.07.2021-08.07.2021
Trnski, Diana ; Gregorić, Maja ; Levanat, Sonja ; Ozretić, Petar ; Rinčić, Nikolina ; Majić Vidaković, Tajana ; Kalafatić, Držislav ; Maurac, Ivana ; Orešković, Slavko ; Sabol, Maja et al. | Utjecaj proteina GLI na regulaciju ekspresije izoformi survivina u karcinomu jajnika // 6. Simpozij – Apoptoza i novotvorine | Zagreb, Hrvatska, 26.03.2019-26.03.2019
Publikacije - ocjenski radovi
Diplomski rad
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Rinčić, Nikolina | Izrada "knock out" stanične linije za gen GLI1 primjenom sustava CRISPR/Cas9 / Sabol, Maja ; Blažević, Sofia Ana (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2018
urn.nsk.hr
Doktorska disertacija
Piteša, Nikolina | Interakcija signalnih puteva RAS/RAF/MAPK i Hedgehog-GLI u rezistenciji na lijekove u staničnim linijama melanoma čovjeka / Maja Sabol (mentor). | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, 2023
Članstva u profesionalnim udrugama / društvima
Federacija europskih biokemijskih društava (FEBS) - član
Hrvatsko društvo za biokemiju i molekularnu biologiju (HDBMB) - član
Hrvatsko društvo za istraživanje raka (HDIR) - član
European Association For Cancer Research (EACR) - član